The comprehensive monograph on the Interconnected Systems Framework (ISF) provides a framework for a cross-system problem-solving team, comprised of key stakeholders in education and mental health systems, youth and families, that works to ensure earlier access for children and youth to high quality care. It provides a blueprint for the teams to examine community and school level data and develop action plans to implement evidence-based practices that meet a community’s identified needs. The development of the ISF was supported by the U.S. Office of Special Education Programs, the Maternal and Child Health Bureau of the U.S. Department of Health and Human Services, the Technical Assistance Center on PBIS, the IDEA Partnership, the National Community of Practice on Collaborative School Behavioral Systems and the University of Maryland Center for School Mental Health. It also reflects experiences of state and district school leaders from Illinois, Maryland, Montana, New York, Pennsylvania, and South Carolina.